[CARPA] Influenza vaccination in pregnancy
Malcolm McDonald
Malcolm.McDonald at menzies.edu.au
Thu Oct 2 13:35:04 EST 2008
1. Influenza has an increased morbidity and mortality in pregnancy.
2. Influenza has an increased morbidity and mortality in the first
year of life.
3. Inactivated influenza vaccination is safe in pregnancy.
4. Inactivated influenza vaccination is currently recommended in
pregnancy (The Australian Immunisation Handbook) to protect the mother.
5. In a recently published study in a setting with year-round
influenza (similar to the NT), inactivated influenza vaccine given in
pregnancy substantially reduced proven influenza in infants < 6 months
of age and averted a third of all febrile respiratory illness in
mothers and young infants.
6. We recommended that health practitioners include inactivated
influenza vaccination for pregnant women as part of routine antenatal
care.
References
* The Australian Immunisation Handbook 9th Edition 2008
* Rothberg et al. Complications of viral influenza. Am J
Med 2008; 21:258-64
* Zaman K, et al. Effectiveness of maternal influenza
immunization in mothers and infants. N Engl J Med 2008 (ePublished -
PMID: 18799552)
Dr Malcolm McDonald - Specialist Outreach Physician, Menzies School of
Health Research
Prof Anne Chang - Head, Division of Child Health, Menzies School of
Health Research
Dr Vicki Krause - Director, Centre for Disease Control, DHF (NT)
Dr Ros Webby - Head of Immunisation, Centre for Disease Control, DHF
(NT)
Ms Chris Nagy - Immunisation Project Officer, Centre for Disease
Control, DHF (NT)
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